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邓楠楠长聘(教轨)副教授

电子邮件:n.deng@sjtu.edu.cn
通讯地址:上海市东川路800号上海交通大学化学C楼609
个人主页: https://sites.google.com/view/denglab/home

  • 教育背景

    2009-2014,四川大学,工学博士,导师:褚良银教授

    2005-2009,四川大学,工学学士,导师:褚良银教授

  • 工作经历

    2026-至今, 上海交通大学,长聘副教授

    2019-2025,上海交通大学,长聘教轨副教授,博士生导师

    2017-2019,美国哈佛大学,博士后,合作导师:Prof. George M. Whitesides

    2014-2017,荷兰内梅亨大学,博士后/玛丽居里学者,合作导师:Prof. Wilhelm T.S. Huck

  • 研究方向

    本课题组主要从事人工细胞、活性软物质、微纳米机器人、液-液相分离和微流控技术相关的基础研究和技术开发,具体包括:

    1)人工细胞和原始细胞(Artificial cells & Protocells)

    2)光流体/活性软物质 (Photofluidis & Active soft matter)

    3)液液相分离(ATPS、Coacervates、DNA液滴等)

    4)液滴微流控技术 

    5)  微纳米机器人

    6)单细胞基因测序建库技术

  • 科研项目

    主持国家自然科学基金青年项目、面上项目(2)、国家青年千人项目、上海市面上项目、四川省面上项目、四川省天府峨眉计划、上交绍兴研究院开放基金,共同主持上交医工交叉青年、重点项目和若干横向课题等,参与基金委重大项目、上海市重大专项等。

  • 代表性论文专著

    独立工作后代表性通讯作者论文:

    Nature Materials (1), Nature Chemical Engineering (2), JACS (1), Angew. Chem. (3), Sci. Adv. (2), Nat. Commun. (1)., CCS Chem. (1), Adv. Mater. (2), Chem. Soc. Rev. (1)等。


    Full publication list:

    https://scholar.google.com/citations?user=6i5ARiQAAAAJ&hl=en


    Selected Publicaitons:


    Co-first author; *Corresponding author 


    25) Chun-Yan Fang, Nan-Nan Deng,Synthetic Microbial Ecosystems for Stable Flow Biocatalysis. Angewandte Chemie International Edition, 2026, e6873420. (Invited)

    https://doi.org/10.1002/anie.6873420

    1770965271208673.png


    24) Qiang Cao, Ping Zhang, Hong-Yu Yang, Ting-Yuan Hu, Da-Wei Pan, Xiao-Jie Ju, Zhuang Liu, Rui Xie, Nan-Nan Deng,* Wei Wang,* Liang-Yin Chu. 

    Nonequilibrium Surfactant Partitioning Drives Self-nanoemulsification for Scalable Nanocarrier Production. Nature Chemical Engineering, 2026, accepted.


    1770965135860262.png


    23) Jin-Ying Qi, Qi-Hong ZhaoNan-Nan Deng.* A Photo-active Synthetic Cell. CCS Chemistry, 2026, 8, 202–209. (Cover) 

    https://doi.org/10.31635/ccschem.025.202506237


    1767333798256826.png


    22) Ming-Di Gao, Chao-Yang Guan, Jia-Yao Wang, Jin-Ying Qi and Nan-Nan Deng.*  Thermally Switchable Photoactivity in Azobenzene-Functionalized DNA Condensates.  Advanced Materials, 2026, 38, e18318.2026, 38, e18318

    37, 2508047https://doi.org/10.1002/adma.202518318


    1764854472675977.png


    21) Jia-Yao Wang, Ming-Di Gao, Chao-Yang Guan, Jin-Ying Qi, Nan-Nan Deng.* Ultraviolet and Visible Light-Responsive RNA Photofluids. Angewandte Chemie International Edition, 2025, 64, e202515264. 

    https://doi.org/10.1002/anie.202515264


    1757745355163185.png


    20) Zhen-Hong Luo, Xuan-Yan He, Nan-Nan Deng.* Monodisperse Giant Unilamellar Niosomes as Minimal Synthetic Cells. Journal of the American Chemical Society, 2025, 147, 27081−27088. 

    https://doi.org/10.1021/jacs.5c09950


    1752284428238955.png


    19) Muhammad Umar Farooq, Charles H. Lawrie, Nan-Nan Deng.* Solving Mazes of Organelle-targeted Therapies with DNA Nanomachines. Advanced Materials, 2025, 37, 250804737, 2508047.

    https://doi.org/10.1002/adma.202508047


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    18) Zhenhua Li,+ Qing Liu,+ Han Ding, Zhuojun Meng, Qi-Hong Zhao, Nan-Nan Deng,* Lifei Zheng.* Static and transient vacuolation in protein-based coacervates induced by charged amino acids. Nature Communications, 2025, 16, 5837. 

    https://doi.org/10.1038/s41467-025-61340-w


    Screen Shot 2025-07-01 at 20.45.32.png


    17) Qi-Hong Zhao, Jin-Ying Qi, Nan-Nan Deng.* DNA photofluids show life-like motion. Nature Materials, 2025, 24 (6), 935−944. 

    https://doi.org/10.1038/s41563-025-02202-0. (free access: https://rdcu.be/eg1x9)


    1752284673735646.png

         News & Views:

         Brigitta Dúzs,* Andreas Walther.* DNA droplets shuffle in the spotlight. Nature Materials, 2025, 24, 816−817. 

         https://doi.org/10.1038/s41563-025-02226-6


    16) Dong‐Yu Li, Nan‐Nan Deng.* Transient Structural Coloration During Dewetting Transition of Water‐In‐Oil‐In‐Water Droplets. Small, 2025, 2503654. 

    https://doi.org/10.1002/smll.202503654

    Screen Shot 2025-06-06 at 18.21.34.png


    15) Yao-Yao Su, Da-Wei Pan,* Tao-Xian Zhang, Rui Xie, Xiao-Jie Ju, Zhuang Liu, Nan-Nan Deng,* Wei Wang,* Liang-Yin Chu. Wetting-induced Interfacial Instability: A Mechanism for Droplet Emission at Air-liquid Interfaces. Science Advances, 2025, 11(12), ads1065.

     https://www.science.org/doi/10.1126/sciadv.ads1065 

    1742433383601746.png


    14) Jia-Qi Tian, Nan-Nan Deng.* Dynamic satellite-parent liposome networks for quantitative microreactions. Chemical Science, 2024,

    15, 19619−19625. 

    https://doi.org/10.1039/D4SC04925J.  

    1730855078337733.png


    13) Jia-Qi Tian, Mu-Yueh Chang, Chen Chen, Zhen-Hong Luo, Wilhelm T. S. Huck, Nan-Nan Deng.* Interfacial Energy-mediated Bulk Transport across Artificial Cell Membranes. Nature Chemical Engineering, 2024, 1 (7)450–461. (Cover)

    pages https://www.nature.com/articles/s44286-024-00088-4 (Free PDF access link: rdcu.be/dMKyA)


    1721914898788850.png

          News & views: 

           Atul N. Parikh.* Controlling transport across artificial cell membranes. Nature Chemical Engineering, 2024, 1 (7), 447–449.

          https://www.nature.com/articles/s44286-024-00091-9


    12) Zhen-Hong Luo, Chen Chen, Qi-Hong Zhao, Nan-Nan Deng.* Functional Metal-phenolic Cortical Cytoskeleton for Artificial Cells. Science Advances, 2024, 10, eadj4047. 

    https://www.science.org/doi/10.1126/sciadv.adj4047

    1705386652437198.png


    11) Dong-Yu Li, Wei Wang, Liang-Yin Chu, and Nan-Nan Deng.* Tunable Structural Coloration in Eccentric Water-in-Oil-in-Water Droplets. Nano Letters, 2023, 23, 9657−9663. (Supplementary Cover)

    https://doi.org/10.1021/acs.nanolett.3c02119.

    1721915058404304.png


    10) Mu-Yueh Chang, Hirotaka Ariyama, Wilhelm T. S. Huck,* Nan-Nan Deng.* Division in synthetic cells. Chemical Society Review2023, 52, 3307−3325. 

    https://doi.org/10.1039/D2CS00985D

    Screen Shot 2023-05-26 at 13.31.24.jpg


    9) Qi-Hong Zhao,+ Fang-Hao Cao,+ Zhen-Hong Luo, Wilhelm TS Huck, Nan-Nan Deng.* Photoswitchable Molecular Communication between Programmable DNA‐based Artificial Membraneless Organelles. Angewandte Chemie International Edition, 2022, 61, e202117500. 

    https://doi.org/10.1002/anie.202117500

    1644379270210726.png




    Before SJTU:

    8) Nan-Nan Deng,* Mahesh Vibhute, Lifei Zheng, Hui Zhao, Maaruthy Yelleswarapu, Wilhelm TS Huck.* Macromolecularly crowded protocells from reversibly shrinking monodisperse liposomes. Journal of the American Chemical Society, 2018, 140, 7399−7402. 

    https://doi.org/10.1021/jacs.8b03123

    1644378358127305.png


    7) Nan-Nan Deng,* Wilhelm T. S. Huck.* Microfluidic formation of monodisperse coacervate organelles in liposomes. Angewandte Chemie International Edition, 2017, 56, 9736−9740. 

    https://doi.org/10.1002/anie.201703145

    1644378732860721.png


    6) Nan-Nan Deng, Maaruthy Yelleswarapu, Life Zheng, Wilhelm T. S. Huck.* Microfluidic assembly of monodisperse vesosomes as artificial cell models. Journal of the American Chemical Society, 2017, 139, 587−590. (Front Cover, highlighted by JACS Spotlight) 

    https://doi.org/10.1021/jacs.6b10977

    1644378831152762.png


    5) Nan-Nan Deng, Maaruthy Yelleswarapu, Wilhelm T. S. Huck.* Monodisperse uni- and multi-compartment liposomes. Journal of the American Chemical Society, 2016, 138, 7584−7591. 

    https://doi.org/10.1021/jacs.6b02107

    1644378923458374.png


    4) Nan-Nan Deng, Wei Wang, Xiao-Jie Ju, Rui Xie, Liang-Yin Chu.* Spontaneous transfer of droplets across microfluidic laminar interfaces. Lab on a Chip, 2016, 16, 4326−4332. (Front Cover)  

    https://pubs.rsc.org/en/content/articlelanding/2016/lc/c6lc01022a

    1708263974709911.png


    3) Nan-Nan Deng, Wei Wang, Xiao-Jie Ju, Rui Xie, David A. Weitz, Liang-Yin Chu.* Wetting-induced formation of controllable monodisperse multiple emulsions in microfluidics. Lab on a Chip, 2013, 13, 4047−4052. (Back Cover)  

    https://pubs.rsc.org/en/content/articlelanding/2013/lc/c3lc50638j


    2) Nan-Nan Deng, Shao-Xing Sun, Wei Wang, Xiao-Jie Ju, Rui Xie, Liang-Yin Chu.* A novel surgery-like strategy for droplet coalescence in microchannels. Lab on a Chip, 2013, 13, 3653−3657.   

    https://pubs.rsc.org/en/content/articlelanding/2013/lc/c3lc50533b


    1) Nan-Nan Deng, Zhi-Jun Meng, Rui Xie,* Xiao-Jie Ju, Chuan-Lin Mou, Wei Wang, Liang-Yin Chu.* Simple and cheap microfluidic devices for preparation of monodisperse emulsions. Lab on a Chip, 2011, 11, 3963−3969. (Back Cover)  

    https://pubs.rsc.org/en/content/articlelanding/2011/lc/c1lc20629j


  • 学术兼职

    Reviewers for

    Nature Nanotechnology, Nature Chemistry, Nature Chemical Engineering, JACS, Nature Communications, Angew. Chem., Chem, ACS Nano, Chem. Sci., Chem. Comm., Lab on a Chip, AFM, Small, AIChE Journal, etc.


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  • 荣誉奖励

    2024 上海交通大学优秀班主任

    2024 上海交通大学青教赛 二等奖

    2021 天府峨眉计划

    2021 全球华人化工学会 “未来化工学者”

    2019 国家高层次海外人才计划

    2015-2017 欧盟玛丽居里学者

    2014 四川大学优秀博士毕业生

    2013 博士研究生国家奖学金

    2013 赢创奖学金

    2012 宝钢奖学金

  • 教学工作

    本科生:《化工原理基础》(致远学院),《化工原理基础》(太阳集团2138登录入口)

    研究生:《绿色化工》

    前沿课:《化学工程与技术前沿专题》、《化学生物学》

  • 人才需求

    招收2026年秋季入学博士生(申请-考核)

    具体要求:

    1. 具有高分子、超分子组装或多酶催化等相关背景,已经/即将获得硕士学位;

    2. 有高水平论文发表经历(审稿中亦可);

    3. 踏实勤奋、有学术志向。

    招收博士后若干名

    1. 教育经历:具有(即将获得)博士学位;

    2. 学科方向:高分子、软物质、超分子自组装、生物化工、微生物、合成生物学、化学生物学、微化工和微流控技术等相关相近方向。

    联系方式: n.deng@sjtu.edu.cn


    欢迎有志于科学研究的本科生进入实验室进行科研训练。



地址:上海市东川路800号 200240
电话:021-54742893
E-mail:sjtuscce@sjtu.edu.cn

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